Here is a rather technical article. People who think they can refute it can also deal with the fifty supporting links:
In the same way that species are not static, neither are genomes. They change over time; sometimes randomly, sometimes in preplanned pathways, and sometimes according to instruction from pre-existing algorithms. Irrespective of the source, we tend to call these changes ‘mutations’. Many evolutionists use the existence of mutation as evidence for long-term evolution, but the examples they cite fall far short of the requirements of their theory. Many creationists claim that mutations are not able to produce new information. Confusion about definitions abounds, including arguments about what constitutes a mutation and the definition of ‘biological information’. Evolution requires the existence of a process for the invention of new information from scratch. Yet, in a genome operating in at least four dimensions and packed with meta-information, potential changes are strongly proscribed. Can mutations produce new information? Yes, depending on what you mean by ‘new’ and ‘information’. Can they account for the evolution of all life on Earth? No!You can read the rest of "Can Mutations Create New Information?", here.